CSHL Leading Stand
Title: Transposable elements as catalysts of cellular innovation
Meeting: 2018 Transposable Elements
Date: 11/01/2018
1:14:13
How biology optimizes both specificity and efficiency—Single molecule studies of ubiquitylation
46:02
Avian genomics a decade after the publication of the chicken genome sequence
1:02:30
Considering the digital Universe of data to better diagnose and treat patients
1:01:26
Gene Regulatory Networks
1:27:27
"Edgetics"
1:05:20
Mechanisms of transcriptional precision in the Drosophila embryo
50:05
Understanding the biochemical and biophysical basis for genome organization
45:48
Larry Katz Lecture
56:50
Oligodendroglial metabolism and the support of axonal intergrity
51:47
Structural epigenomics (precision mapping of the chromatin landscape)
45:56
Keynote address
42:37
Natural populations of Caenorhabditis and studies on apparent and cryptic phenotypic variation
1:06
Neuronal mechanism of state control in Drosophila melanogaster
46:50
Ubiquitination regulated RIPK1 activation controls apoptosis and necroptosis
57:56
Exploiting DNA sequencing technology for high-throughput neuroanatomy
1:05:26
Two decades of sonic hedgehog
48:25
Stem cells and epigenetic regulation in development and disease
1:02:12
The stabilization of cell differentiation
1:46:56
Analysis of the p53 pathway in zebrafish
55:06
Regulation of proteasome function in normal and disease states
52:16
Ubiquitin-like proteins:From conjugation to recognition
53:45
Celebrating the ubiquitin family;diversity of cullin-RING Ubl and Ub ligation mechanisms
53:04
Maintaining proteasome homeostasis
54:15
Ubiquitin and Autophagy Networks
Mapping genome-wide nucleosome dynamics
1:06:19
Transcriptional regulation and metabolism: key elements in the evolution and mechanisms of social life in bees
51:07
Comparative transcriptomics reveals the modular organization of ant phenotypic traits
53:40
The influence of genes and social environment on behavior and social organization
1:06:04
The application of integrative sequencing for precision medicine
56:07
Mendelian randomization:Harnessing genocopy/phenocopy to identify modifiable causes of disease
50:58
From the HGP to Precision Medicine
48:29
Genomic Discovery: Mechanisms of Meiotic Recombination
45:31
Genomic Erosion in Symbiotic Bacteria
1:02:58
Keynote Lecture
41:19
The success strategies of transposable elements that rapidly diversify genomes
50:23
Sex differences in health and disease
1:03:28
Generating and shaping novel action repertoires
54:33
Junk Evolution
52:49
Exocytosis in neurons—Interplay between proteins and lipids
58:44
Mechanisms of protein translocation across membranes
47:18
Targeting CAR to Treat and Prevent Liver Cancer
1:05:23
The influence of immunogenetic variation on HIV disease
1:11:20
T cell death and chronic inflammation: An unexpected link in HIV infection
56:25
Using mouse genetics to study host-virus interactions
1:09:17
40 Years in Retrovirology, a Reminiscence
1:11:39
Keynote Speaker
54:19
Germ line retroviruses-good or bad?
1:08:29
HIV RNAAAAAAA
50:26
The roots of obesity—Mechanisms of lipid synthesis and storage
1:11:52
Why study integration and reverse transcription
1:14:49
Can HIV-1 be eradicated from the individual and the world?
1:18:07
HIV release and infectivity—From ESCRTs to SERINCs
1:01:02
Retroviruses; Some Perspectives
The Genetic Legacy of Neanderthals
58:22
The Logic of Your Immune System
1:03:50
Connecting mind and brain in a computational age
1:01:15
Membrane dynamics and virus entry—From atomic structures to single-molecule movies
46:18
Targeting the aberrant R-Loop accumulation in cancer cells with ATR inhibitors
1:50:48
Osteoarthritis —Understanding a common complex disease
57.11
CryoEM image analysis of macromolecular motor assemblies
55:00
Unveiling the long-held secrets of the 26S proteasome
Tools for studying neurons, the only important cells in the brain
1:05:25
“On the rules of cortical wiring and function, with implications for understanding psychiatric disorders”
47:31
Targeting cancer’s engines, not its drivers
1:18:37
SCAP: Sensor of Membrane Cholesterol
47:28
The evolution of thymic lymphomas in P53 knock-out mice
1:04:44
Manipulating cell death—The discovery and preclinical development of Bcl-2 inhibitors
Oxidative Stress Defenses in Cancer
46:09
1:09:37
Nanoscopy with focused light
49:15
Programmable RNA-guided genome defense in bacteria
Elucidating the interplay between RNA sequence, structure and translation regulation during vertebrate embryogenesis
44:15
Analysis of the role of Spt6 in controlling transcriptional accuracy in yeast
41:42
The dinucleotide CG as a genomic signalling module
48:52
MicroRNAs in aging
56:17
Lost in translation—Moving from de novo mutations to pathophysiology
29:58
Identification and studies of mechano-transduction channels in Drosophila
29:45
Recent studies of potassium channels and a novel family of calcium-activated anion channels and cation channels
43:41
Nucleosome compaction as a regulatory mechanism during development
How systems medicine is changing healthcare
1:20:25
Towards a neuron cell atlas
47:58
Proteopedia—A scientific 'Wiki' bridging the rift between 3D structure and function of biomacromolecules
1:02:37
Imaging cellular structure and dynamics from molecules to organisms
1:01:01
Stem cells and pluripotency—Mechanisms of reprogramming and gene targeting in ES cells and mice
59:39
Visualizing calcium—Insights into quantal synaptic transmission and cortex glial function
52:46
Circuit mechanisms for flexible sensorimotor processing in Drosophila
59:23
De novo lipogenesis induced by ER stress is essential for hepatic steatosis and its progression to NASH
Posttranscriptional regulation of mitochondrial gene expression
49:51
PERSONALIZED CANCER GENOMICS: IMPACT AND IMPLICATIONS
1:08:44
Super-enhancers and the control of cell identity and disease
53:28
An integrated 3D network controls a bacterial cell cycle
52:01
Synergistic targeting therapies against oncoproteins for acute myeloid leukemia
45:02
The era of the cancer epigenome: Dissecting the biological and translational implications
47:10
Causes and consequences of microRNA dysregulation in cancer
1:06:24
New insight into the neurobiology of depression
46:40
Stories from the Supplement
Transposable elements as catalysts of cellular innovation
Retrotransposon storm hypothesis of ALS—The dangers of a Collyer's genome
Evolutionary outcomes of CRISPR-anti-CRISPR conflict
58:12
“A protein-domain approach for the analysis of disease mutations”
1:01:34
“Post-procrustean bioinformatics”
1:33:12
Global exchange of human genetic data for medicine and research
Population genetic models for human associated microbes
Lessons learned—Reflections on some research projects in computational biology, where they came from, and where they went
59:35
Progress and perspectives of osteoporosis treatment
1:27:53
"Dissection of the regulatory trajectory for early T-cell lineage commitment"
1:13:29
"Optical tools for analyzing and repairing complex biological systems"
Interrogating the robustness of gene regulatory circuits by RACIPE
50:11
Some thoughts on ever more available sequencing
35:48
The Beery Family Journey—A sequencing success
50:10
MicroRNAs can function as ligands for TLR and regulate the interactions between cancer cells and their microenviroment
33:07
My daughter's DNA and every little thing about her?
45:06
Three cautions about personalized medicine
55:25
Harnessing immunity to prevent and treat HIV infection
36:11
Truth and consequences—Reflections on ethical issues in synthetic biology
42:29
Mechanisms of selective gene silencing
46:23
Pushing the scale of Genetic Engineering
40:36
Gut morphogenesis—From physical forces to localization of stem cells
1:06:51
"Using ancient genomes and model systems to study uniquely human phenotypes"
56:21
"3D models of the human brain—What are the ethical concerns and how should they be addressed?"
1:01:11
Genomics of hematopoietic gene regulation
1:12:49
The Glymphatic System
53:57
How do you get rat research support in world of GWAS and whole genome sequencing in humans?