Keynote Lecture Series

Michael Levine

1:05:20

Mechanisms of transcriptional precision in the Drosophila embryo

Weizhe Hong

45:48

Larry Katz Lecture

Bob Kingston

56:50

Oligodendroglial metabolism and the support of axonal intergrity

Marie-Anne Felix

42:37

Natural populations of Caenorhabditis and studies on apparent and cryptic phenotypic variation

Philip Ingham

1:05:26

Two decades of sonic hedgehog

John Gurdon

1:02:12

The stabilization of cell differentiation

David Lane

1:46:56

Analysis of the p53 pathway in zebrafish

Steven Henikoff

Mapping genome-wide nucleosome dynamics

Susan Wessler

41:19

The success strategies of transposable elements that rapidly diversify genomes

Maxine Linial

1:09:17

40 Years in Retrovirology, a Reminiscence

Jonathan Stoye

54:19

Germ line retroviruses-good or bad?

John Mellors

1:14:49

Can HIV-1 be eradicated from the individual and the world?

Stefan Lohmander

1:50:48

Osteoarthritis —Understanding a common complex disease

Charles Sherr

46:09

Keynote Lecture

Jennifer Doudna

49:15

Programmable RNA-guided genome defense in bacteria

Adrian Bird

41:42

The dinucleotide CG as a genomic signalling module

Yuh-Nung Jan

29:58

Identification and studies of mechano-transduction channels in Drosophila

Lily Jan

29:45

Recent studies of potassium channels and a novel family of calcium-activated anion channels and cation channels

Lucy Shaprio

53:28

An integrated 3D network controls a bacterial cell cycle

Zhu Chen

52:01

Synergistic targeting therapies against oncoproteins for acute myeloid leukemia

Stephan Baylin

45:02

The era of the cancer epigenome: Dissecting the biological and translational implications

Carlo Croce

47:10

Causes and consequences of microRNA dysregulation in cancer

Retta Beery

35:48

The Beery Family Journey—A sequencing success

Carlo Croce

50:10

MicroRNAs can function as ligands for TLR and regulate the interactions between cancer cells and their microenviroment

Maynard Olson

45:06

Three cautions about personalized medicine

Clifford Tabin

40:36

Gut morphogenesis—From physical forces to localization of stem cells

Eric Schadt

1:02:30

Considering the digital Universe of data to better diagnose and treat patients

Eric Lander

1:02:58

Keynote Lecture

Tom Rapoport

58:44

Mechanisms of protein translocation across membranes

Reinhard Jahn

52:49

Exocytosis in neurons—Interplay between proteins and lipids

Warner Greene

1:11:20

T cell death and chronic inflammation: An unexpected link in HIV infection

Ben Berkhout

1:08:29

HIV RNAAAAAAA

Robert Farese

50:26

The roots of obesity—Mechanisms of lipid synthesis and storage

Hidde Ploegh

58:22

The Logic of Your Immune System

Edmund Rolls

1:05:25

“On the rules of cortical wiring and function, with implications for understanding psychiatric disorders”

Michael Brown

1:18:37

SCAP: Sensor of Membrane Cholesterol

Stefan Hell

1:09:37

Nanoscopy with focused light

Rudolf Jaenisch

1:01:01

Stem cells and pluripotency—Mechanisms of reprogramming and gene targeting in ES cells and mice

Leroy Hood

How systems medicine is changing healthcare

Jan Melom

59:39

Visualizing calcium—Insights into quantal synaptic transmission and cortex glial function

Joel Sussman

47:58

Proteopedia—A scientific 'Wiki' bridging the rift between 3D structure and function of biomacromolecules

Richard A. Young

1:08:44

Super-enhancers and the control of cell identity and disease

Eric Nestler

1:06:24

New insight into the neurobiology of depression

Lior Pachter

46:40

Stories from the Supplement

Hugh Reinhoff

33:07

My daughter's DNA and every little thing about her?

Richard Durbin

50:11

Some thoughts on ever more available sequencing

Michel Nussenzweig

55:25

Harnessing immunity to prevent and treat HIV infection

Ross Hardison

1:01:11

Genomics of hematopoietic gene regulation

Jacob Howard

53:57

How do you get rat research support in world of GWAS and whole genome sequencing in humans?

David Burt

46:02

Avian genomics a decade after the publication of the chicken genome sequence

Ramon Parsons

45:56

Keynote address

Hidehiko Inagaki

1:06

Neuronal mechanism of state control in Drosophila melanogaster

Peter Donnelly

48:29

Genomic Discovery: Mechanisms of Meiotic Recombination

Nancy Moran

45:31

Genomic Erosion in Symbiotic Bacteria

Mary Carrington

1:05:23

The influence of immunogenetic variation on HIV disease

David Moore

47:18

Targeting CAR to Treat and Prevent Liver Cancer

Rui Costa

1:03:28

Generating and shaping novel action repertoires

Stephen Harrison

1:01:15

Membrane dynamics and virus entry—From atomic structures to single-molecule movies

Keiichi Namba

57.11

CryoEM image analysis of macromolecular motor assemblies

Wolfgang Baumeister

55:00

Unveiling the long-held secrets of the 26S proteasome

Loren Looger

Tools for studying neurons, the only important cells in the brain

Gerard Evan

47:31

Targeting cancer’s engines, not its drivers

Arnold Levine

47:28

The evolution of thymic lymphomas in P53 knock-out mice

Fred Winston

44:15

Analysis of the role of Spt6 in controlling transcriptional accuracy in yeast

Toshio Matsumoto

59:35

Progress and perspectives of osteoporosis treatment

Paul Bieniasz

1:11:39

Keynote Speaker

David Haussler

1:33:12

Global exchange of human genetic data for medicine and research

Laurie Zoloth

36:11

Truth and consequences—Reflections on ethical issues in synthetic biology

Christopher Voight

46:23

Pushing the scale of Genetic Engineering

Maiken Nedergaard

1:12:49

The Glymphatic System

Marc Kirschner

1:14:13

How biology optimizes both specificity and efficiency—Single molecule studies of ubiquitylation

Ivan Dikic

54:15

Ubiquitin and Autophagy Networks

Arul Chinnaiyan

1:06:04

The application of integrative sequencing for precision medicine

Gene Robinson

1:06:19

Transcriptional regulation and metabolism: key elements in the evolution and mechanisms of social life in bees

Judith Korb

51:07

Comparative transcriptomics reveals the modular organization of ant phenotypic traits

Laurent Keller

53:40

The influence of genes and social environment on behavior and social organization

Brenda Schulman

53:45

Celebrating the ubiquitin family;diversity of cullin-RING Ubl and Ub ligation mechanisms

George Davey Smith

56:07

Mendelian randomization:Harnessing genocopy/phenocopy to identify modifiable causes of disease

Francis Collins

50:58

From the HGP to Precision Medicine

Susan Ross

56:25

Using mouse genetics to study host-virus interactions

Svante Paabo

The Genetic Legacy of Neanderthals

Frank Slack

48:52

MicroRNAs in aging

Eric Shoubridge

Posttranscriptional regulation of mitochondrial gene expression

Alfred Goldberg

55:06

Regulation of proteasome function in normal and disease states

Alan Rein

1:01:02

Retroviruses; Some Perspectives

Robert Kingston

43:41

Nucleosome compaction as a regulatory mechanism during development

Aviv Regev

1:20:25

Towards a neuron cell atlas

Mingyang Lu

Interrogating the robustness of gene regulatory circuits by RACIPE

Marian Walhout

1:01:26

Gene Regulatory Networks

Marc Vidal

1:27:27

"Edgetics"

Anne Bertolotti

53:04

Maintaining proteasome homeostasis

Christopher Lima

52:16

Ubiquitin-like proteins:From conjugation to recognition

Andrew Clark

54:33

Junk Evolution

Stephen Hughes

1:11:52

Why study integration and reverse transcription

Craig Thompson

1:04:44

Manipulating cell death—The discovery and preclinical development of Bcl-2 inhibitors

Raphael Cohn

52:46

Circuit mechanisms for flexible sensorimotor processing in Drosophila

Michael Karin

59:23

De novo lipogenesis induced by ER stress is essential for hepatic steatosis and its progression to NASH

Elaine R. Mardis

49:51

PERSONALIZED CANCER GENOMICS: IMPACT AND IMPLICATIONS

Maricel Kann

58:12

“A protein-domain approach for the analysis of disease mutations”

Lior Pachter

1:01:34

“Post-procrustean bioinformatics”

Edward Boyden

1:13:29

"Optical tools for analyzing and repairing complex biological systems"

Ellen Rothenberg

1:27:53

"Dissection of the regulatory trajectory for early T-cell lineage commitment"

Svante Paabo

1:06:51

"Using ancient genomes and model systems to study uniquely human phenotypes"

Insoo Hyun

56:21

"3D models of the human brain—What are the ethical concerns and how should they be addressed?"

Geeta Narlikar

50:05

Understanding the biochemical and biophysical basis for genome organization

Steven Henikoff

51:47

Structural epigenomics (precision mapping of the chromatin landscape)

Junying Yuan

46:50

Ubiquitination regulated RIPK1 activation controls apoptosis and necroptosis

Justus Kebschull

57:56

Exploiting DNA sequencing technology for high-throughput neuroanatomy

Rudolf Jaenisch

48:25

Stem cells and epigenetic regulation in development and disease

David Page

50:23

Sex differences in health and disease

Craig Pikaard

42:29

Mechanisms of selective gene silencing

Henrich Gottlinger

1:18:07

HIV release and infectivity—From ESCRTs to SERINCs

P.Read Montague

1:03:50

Connecting mind and brain in a computational age

Lee Zou

46:18

Targeting the aberrant R-Loop accumulation in cancer cells with ATR inhibitors

Joan Brugge

Oxidative Stress Defenses in Cancer

Antonio Giraldez

Elucidating the interplay between RNA sequence, structure and translation regulation during vertebrate embryogenesis